Expression of programmed death-1 (PD-1) in sentinel lymph nodes of breast cancer
نویسندگان
چکیده
منابع مشابه
intra-operative assessment of sentinel lymph nodes in breast cancer
lymph node status remains an important prognostic indicator for survival in breast cancer. sentinel lymph node biopsy has become the standard method of assessment of clinically node negative breast cancers. economic implications as well as patient related factors have lead to the development a number of intra-operative techniques. review of the emerging trends in the last 4 years show that alth...
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Background: Intra-operative molecular diagnostic assays are currently used for the detection of lymph node metastases. The objective of this study was to find new biomarkers to improve diagnostic accuracy in the detection of metastatic axillary lymph nodes in breast cancer patients. Methods: We applied an absolute quantitative real-time RT-PCR to quantitate the expression of CK19, KLK11, and CL...
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Angiosarcomas are rare malignant endothelial-cell tumors of vascular or lymphatic origin, and are among the most aggressive subtypes of soft-tissue sarcomas. The prognosis is poor and treatment is challenging in many cases. PD-1/PD-L1 pathway plays a critical role in immune escape of tumor cells. Recent studies described that PD-L1 is widely expressed in various types of cancer, providing the b...
متن کاملIntraoperative Assessment of Sentinel Lymph Nodes in Breast Cancer
Despite this, sentinel lymph node biopsy is considered as a standard method of assessment of clinically node-negative breast cancers. Economicimplications as well as patient related factors have led to the development a number of intraoperative techniques. Review of the emerging trends of practice in the last 4 years show that although routine histological examination remains the gold standard ...
متن کاملIntraoperative assessment of sentinel lymph nodes in breast cancer.
BACKGROUND Sentinel lymph node biopsy (SLNB) reduces the morbidity of axillary clearance and is the standard of care for patients with clinically node-negative breast cancer. The ability to analyse the sentinel node during surgery enables a decision to be made whether to proceed to full axillary clearance during primary surgery, thus avoiding a second procedure in node-positive patients. METH...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2017
ISSN: 0923-7534
DOI: 10.1093/annonc/mdx697.007